Psychoacoustics in EAS users

• Investigation of psychoacoustic electric-acoustic masking for combined EAS
• The effect of ES on acoustic hearing if electric and acoustic stimuli are presented simultaneously.
• The effect of AS on electric hearing if electric and acoustic stimuli are presented simultaneously.

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Electrophysiological measurements in EAS users

• Electrophysiological measurements are used to examine electric-acoustic interaction in EAS users.
• Telemetry capabilities of the CI systems are used to derive intracochlear electrocochleography in EAS users.
• Cochlear microphonic (CM) and auditory nerve neurophonic (ANN) potentials, recorded in response to AS, ES, and in response to combined EAS are used to determine peripheral electric-acoustic interaction electrophysiologically.

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Sound coding for EAS

• Development and evaluation of sound coding for EAS users conveying low-frequency information of speech electrically to improve the speech perception for ES alone.
• Investigation of EAS fittings to optimize speech perception for EAS users.

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Computational modelling for EAS

• Development of 3D models of the cochlea for ES and EAS
• Models of neural coding in auditory nerve fibers in response to ES, AS, and EAS
• Models of electrophysiological responses such as the electrically or acoustically evoked compound action potential to investigate the effect of electric-acoustic interaction on these measures
• Neural networks to emulate psychoacoustic experiments or speech perception of EAS users in different neural health conditions
• See also: Computational Modelling

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Electric Acoustic Integration

• Investigation of central electric acoustic interaction through speech understanding performance and cortical EEG measurements;
• Investigation of peripheral electric acoustic interaction through electric-acoustic pitch matching and measurement of auditory brainstem responses;
• Optimization of the CI fitting using the measurements of central and peripheral electric acoustic interaction.

Abbreviations: * ES: electric stimulation * AS: acoustic stimulation * EAS: electric-acoustic stimulation

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READIHEAR: Rehabilitation and Diagnosis of Hearing Loss based on Electric Acoustic Interaction

• Investigates electric–acoustic interactions in the auditory pathway, from cochlea to cortex, to better understand combined stimulation effects.
• Aims to advance diagnostics and therapies by laying the groundwork for next-generation devices for hearing loss treatment.
• Funding: EU Grant agreement ID: 101044753
• Further information: READIHEAR.

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Team Members

• Benjamin Krüger
• Daniel Kipping
• Hanna Dolhopiatenko
• Franklin Alvarez
• Patrick Hinz
• Yixuan Zhang
• Robert Hart

Collaborators

• Yang-Soo Yoon

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Publications

• D. Kipping, Y. Zhang, and W. Nogueira (2024): "A Computational Model of the Electrically or Acoustically Evoked Compound Action Potential in Cochlear Implant Users with Residual Hearing". IEEE Transactions on Biomedical Engineering.
• D. Kipping, W. Nogueira (2022): "A Computational Model of a Single Auditory Nerve Fiber for Electric-Acoustic Stimulation". J. Assoc. Res. Otolaryngol.
• B. Krüger, A. Büchner, and W. Nogueira (2022): "Phantom stimulation for cochlear implant users with residual low-frequency hearing". Ear and Hearing.
• B. Krüger, A. Büchner, T. Lenarz, and W. Nogueira (2020): "Electric-acoustic interaction measurements in cochlear-implant users with ipsilateral residual hearing using electrocochleography". J. Acoust. Soc. Am., vol. 147, p. 350.
• B. Krüger, A. Büchner, T. Lenarz, and W. Nogueira (2020): "Amplitude growth of intracochlear electrocochleography in cochlear implant users with residual hearing". J. Acoust. Soc. Am., vol. 147, no. 2, pp. 1147–1162.
• D. Kipping, B. Krüger, W. Nogueira (2020): "The role of electroneural versus electrophonic stimulation on psychoacoustic electric-acoustic masking in cochlear implant users with residual hearing". Hearing Research 395, 108036.
• W. Nogueira, B. Krüger, A. Büchner, E. Lopez-Poveda (2018): "Contralateral suppression of human hearing sensitivity in single-sided deaf cochlear implant users". Hearing Research 2019 Mar 1; 373:121-129.
• M. Imsiecke, B. Krüger, A. Büchner, T. Lenarz, W. Nogueira (2018): "Electric-acoustic forward masking in cochlear implant users with ipsilateral residual hearing". Hearing Research 2018 Jul; 364:25-37.
• B. Krüger, A. Büchner, W. Nogueira (2017): "Simultaneous masking between electric and acoustic stimulation in cochlear implant users with residual low-frequency hearing". Hearing Research.

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Contact
Head of Research Group:	Prof. Dr.-Ing. Waldo Nogueira
Address:	DHZ-Deutsches HörZentrum Hannover Karl-Wiechert-Allee 3 30625 Hannover
Phone:	+49 (0)511 532 8025
Fax:	+49 (0)511 532 6833
E-Mail:	nogueiravazquez.waldo@mh-hannover.de

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